Microglia Activation–Brain Inflammation and Autism
Brain Inflammation, or neroulogical inflammation, with respects to Autism, has been the topic of a tremendous amount of research out of Johns Hopkins University and other research facilities. Emerging research shows that in Autism, there tends to be a higher prevalence of neuro-inflammatory markers likely affecting individuals on the Autism spectrum more adversely.
In short, there is a cell in the brain or a system in the brain called microglia. Microglia is a part of the immune system function of the brain and the central nervous system. In many individuals with Autism, there appears to be what’s called microglia activation where the microglia become activated, but don’t turn off. They can become activated from a virus or bacteria. They can become activated from a potential chemical reaction. There’s been some cases where it’s shown that certain vaccines may be a contributing factor to microglia activation.
When the system doesn’t turn off, it leads to chronic inflammation and essentially the destruction of what are called synapses. Synapses are the small spaces between nerve cells where neuro-chemicals are transferred from one nerve cell to the next as a communication link. So, we get a chemical reaction across the synapse creating an electrical chemical reaction in the corresponding nerve cell. So, anything that is going to affect the synapse will essentially affect chemical transportation from one brain region to the next and electrical impulse activation in the brain as well.
There isn’t just one thing that causes microglia activation, but it is something that should be on your radar. It is something to consider for your child on the Autism spectrum, something that may be a contributing factor to their overall condition. Whether you feel your child had a vaccine reaction, whether they had an infection at some point where things just never returned to normal, or they’ve had chronic immune problems throughout their life like food sensitivities, gut problems, etc, you could be looking at the potential for microglia activation.
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