Autism Treatment – Reserpine and Respen-A Side Effects
A lot of people have asked about some of the side effects of Reserpine and Respen-a in biomedical autism treatment. Clearly with Reserpine, remember those studies that was done in autistic children in 1957 they were using three to seven milligrams, when the levels got too high, kids became irritable, they became cranky, many of them had excessive sleeping, dry mouth and started to develop actually symptoms of parkinsonism when the levels got way high; ten to twelve milligrams. In levels above what would typically for high blood pressure which is point five milligrams, so above point five milligrams there seems to be an increase association with depression. The reason that would be likely is that you’re stimulating MAO-A activity which is having a metabolic effect on serotonin so therefore you’re over time you’re depleting serotonin levels and if they’re not being replenished than clearly there can be a problem with respects to serotonin balance in the body and clearly there can be a problem leading to depression.
Most of the side effects of Respen and Reserpine seem to likely have to do with low blood calcium. Irritability, agitation, crankiness, within kids muscle aches, fatigue, these types of things which can be associated with low blood calcium. Matter of fact, it was the Respen-A people that really first determined that calcium needed to be taken with Respen-A to help counter some of these side effect issues which were commonly seen with Reserpine at higher dosages and honestly have been seen with Respen-A when kids are not getting enough calcium. One of the things that has come out as well in autism treatment is the use of calcium at a high dose for kids and individuals who are taking Respen-A, and this has been a concern for some doctors in the community. And honestly, I had some questioning about it early on when I first started using this therapy because the general recommendation is use 2,000 mg of calcium in the morning minimally thirty minutes prior to treatment upwards of forty five or sixty minutes before putting the Respen-A patch on to try to get the blood levels of calcium up because it is known that Reserpine can deplete blood calcium levels and this can lead again to some of the irritability, the agitation, the muscle aches, the twitching, and whatnot, the cramps that we have seen. And I have seen this with some kids who were taking this therapy as autism treatment when they weren’t getting enough calcium.
Calcium Supplementation as Autism Treatment
Now, you know that in autism treatment there always is a concern about the potential for too much calcium you’ll lead into calcium imbalances in the body. To date, through my practice, I have seen no issues whatsoever with an over absorption or an over abundance of calcium and this is through checking blood tests, looking at certain calcium levels etc. I have not seen a problem, nor has there been any reported to me from other physicians using this treatment. Nor the individuals at Respen-A have they reported any problems with taking this much calcium.
Now I have had a few kids who have a great intolerance to calcium and that’s a different story, but never have I not seen any blood evidence of it or physiological evidence of calcium toxicity through this therapy. It may have to do with the sure fact that the Respen is having a regulating effect over this calcium and keeping things in the more balanced fashion. So, that’s why the calcium issue in autism treatment has come up is because they had found that there’s a depleting effect on cellular calcium and the need to take calcium along with this therapy to prevent some of those common side effects of irritability, agitation, that can be found with calcium depletion.